131I–anti-CD45 antibody plus busulfan and cyclophosphamide before allogeneic hematopoietic cell transplantation for treatment of acute myeloid leukemia in first remission

In an attempt to improve outcomes for patients with acute myeloid leukemia (AML) after allogeneic hematopoietic cell transplantation (HCT), we conducted a phase 1/2 study in which targeted irradiation delivered by (131)I–anti-CD45 antibody was combined with targeted busulfan (BU; area-under-curve, 6...

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Detalhes bibliográficos
Main Authors: Pagel, John M., Appelbaum, Frederick R., Eary, Janet F., Rajendran, Joseph, Fisher, Darrell R., Gooley, Ted, Ruffner, Katherine, Nemecek, Eneida, Sickle, Eileen, Durack, Larry, Carreras, Jeanette, Horowitz, Mary M., Press, Oliver W., Gopal, Ajay K., Martin, Paul J., Bernstein, Irwin D., Matthews, Dana C.
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895719/
https://ncbi.nlm.nih.gov/pubmed/16254140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2317
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