The expression of 70 apoptosis genes in relation to lineage, genetic subtype, cellular drug resistance, and outcome in childhood acute lymphoblastic leukemia

Childhood acute lymphoblastic leukemia (ALL) consists of various subtypes that respond differently to cytotoxic drugs and therefore have a markedly different clinical outcome. We used microarrays to investigate, in 190 children with ALL at initial diagnosis, whether 70 key apoptosis genes were diffe...

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Hlavní autoři: Holleman, Amy, den Boer, Monique L., de Menezes, Renée X., Cheok, Meyling H., Cheng, Cheng, Kazemier, Karin M., Janka-Schaub, Gritta E., Göbel, Ulrich, Graubner, Ulrike B., Evans, William E., Pieters, Rob
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Hematology 2006
Témata:
Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895621/
https://ncbi.nlm.nih.gov/pubmed/16189266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-07-2930
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