Expression of Pitx2 in stromal cells is required for normal hematopoiesis

Although the expression of Pitx2, a bicoid family homeodomain transcription factor, is highly regulated during hematopoiesis, its function during this process was not documented; we thus studied hematopoiesis in Pitx2-null mice. We found that Pitx2(–/–) embryos display hypoplastic livers with reduce...

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Bibliographische Detailangaben
Hauptverfasser: Kieusseian, Aurélie, Chagraoui, Jalila, Kerdudo, Cécile, Mangeot, Philippe-Emmanuel, Gage, Philip J., Navarro, Nicole, Izac, Brigitte, Uzan, Georges, Forget, Bernard G., Dubart-Kupperschmitt, Anne
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Hematology 2006
Schlagworte:
Hematopoiesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895608/
https://ncbi.nlm.nih.gov/pubmed/16195330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-02-0529
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