SALL4, a novel oncogene, is constitutively expressed in human acute myeloid leukemia (AML) and induces AML in transgenic mice

SALL4, a human homolog to Drosophila spalt, is a novel zinc finger transcriptional factor essential for development. We cloned SALL4 and its isoforms (SALL4A and SALL4B). Through immunohistochemistry and real-time reverse-transcription-polymerase chain reaction (RT-PCR), we demonstrated that SALL4 w...

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Hlavní autoři: Ma, Yupo, Cui, Wei, Yang, Jianchang, Qu, Jun, Di, Chunhui, Amin, Hesham M., Lai, Raymond, Ritz, Jerome, Krause, Diane S., Chai, Li
Médium: Artigo
Jazyk:Inglês
Vydáno: © 2006 by The American Society of Hematology 2006
Témata:
Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895586/
https://ncbi.nlm.nih.gov/pubmed/16763212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-02-001594
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