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Enhanced susceptibility to arterial thrombosis in a murine model of hyperhomocysteinemia

Hyperhomocysteinemia is a risk factor for thrombosis, but the mechanisms are not well defined. We tested the hypothesis that hyperhomocysteinemia accelerates arterial thrombosis in mice. Mice heterozygous for a targeted disruption of the cystathionine β-synthase gene (Cbs(+/–)) and wild-type litterm...

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Hlavní autoři: Dayal, Sanjana, Wilson, Katina M., Leo, Lorie, Arning, Erland, Bottiglieri, Teodoro, Lentz, Steven R.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society of Hematology 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895559/
https://ncbi.nlm.nih.gov/pubmed/16804115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-02-005991
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