Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation

Poor T lymphocyte reconstitution limits the use of haploidentical stem cell transplantation (SCT) because it results in a high mortality from viral infections. One approach to overcome this problem is to infuse donor T cells from which alloreactive lymphocytes have been selectively depleted, but the...

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Main Authors: Amrolia, Persis J., Muccioli-Casadei, Giada, Huls, Helen, Adams, Stuart, Durett, April, Gee, Adrian, Yvon, Eric, Weiss, Heidi, Cobbold, Mark, Gaspar, H. Bobby, Rooney, Cliona, Kuehnle, Ingrid, Ghetie, Victor, Schindler, John, Krance, Robert, Heslop, Helen E., Veys, Paul, Vitetta, Ellen, Brenner, Malcolm K.
Format: Artigo
Jezik:Inglês
Izdano: The American Society of Hematology 2006
Teme:
Plenary Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895537/
https://ncbi.nlm.nih.gov/pubmed/16741253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-02-001909
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