Endothelial catabolism of extracellular adenosine during hypoxia: the role of surface adenosine deaminase and CD26

Extracellular levels of adenosine increase during hypoxia. While acute increases in adenosine are important to counterbalance excessive inflammation or vascular leakage, chronically elevated adenosine levels may be toxic. Thus, we reasoned that clearance mechanisms might exist to offset deleterious...

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Detalhes bibliográficos
Main Authors: Eltzschig, Holger K., Faigle, Marion, Knapp, Simone, Karhausen, Jorn, Ibla, Juan, Rosenberger, Peter, Odegard, Kirsten C., Laussen, Peter C., Thompson, Linda F., Colgan, Sean P.
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895500/
https://ncbi.nlm.nih.gov/pubmed/16670267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-02-001016
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