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Central nervous system involvement in adult acute lymphoblastic leukemia at diagnosis: results from the international ALL trial MRC UKALL XII/ECOG E2993

Outcome of acute lymphoblastic leukemia (ALL) in adults with central nervous system (CNS) disease at diagnosis is unclear. We treated 1508 de novo ALL patients with 2-phase induction and then high-dose methotrexate with l-asparaginase. Patients up to 50 years old in first remission (CR1) with a matc...

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Detalhes bibliográficos
Main Authors: Lazarus, Hillard M., Richards, Susan M., Chopra, Raj, Litzow, Mark R., Burnett, Alan K., Wiernik, Peter H., Franklin, Ian M., Tallman, Martin S., Cook, Lucy, Buck, Georgina, Durrant, I. Jill, Rowe, Jacob M., Goldstone, Anthony H.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895498/
https://ncbi.nlm.nih.gov/pubmed/16556888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-11-4666
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