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Central nervous system involvement in adult acute lymphoblastic leukemia at diagnosis: results from the international ALL trial MRC UKALL XII/ECOG E2993

Outcome of acute lymphoblastic leukemia (ALL) in adults with central nervous system (CNS) disease at diagnosis is unclear. We treated 1508 de novo ALL patients with 2-phase induction and then high-dose methotrexate with l-asparaginase. Patients up to 50 years old in first remission (CR1) with a matc...

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Bibliografiske detaljer
Main Authors: Lazarus, Hillard M., Richards, Susan M., Chopra, Raj, Litzow, Mark R., Burnett, Alan K., Wiernik, Peter H., Franklin, Ian M., Tallman, Martin S., Cook, Lucy, Buck, Georgina, Durrant, I. Jill, Rowe, Jacob M., Goldstone, Anthony H.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Hematology 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895498/
https://ncbi.nlm.nih.gov/pubmed/16556888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-11-4666
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