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Melatonin suppresses macrophage cyclooxygenase-2 and inducible nitric oxide synthase expression by inhibiting p52 acetylation and binding

Melatonin has been shown to be produced by nonpineal cells and possess anti-inflammatory actions in animal models. In the present study, we tested the hypothesis that melatonin suppresses the expression of proinflammatory genes such as cyclooxygenase-2 (COX2) and inducible nitric oxide synthase (INO...

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Bibliografski detalji
Glavni autori: Deng, Wu-Guo, Tang, Shao-Tzu, Tseng, Hui-Ping, Wu, Kenneth K.
Format: Artigo
Jezik:Inglês
Izdano: The American Society of Hematology 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895491/
https://ncbi.nlm.nih.gov/pubmed/16609073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-09-3691
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