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Adenosine N1-oxide inhibits vaccinia virus replication by blocking translation of viral early mRNAs.

Adenosine N1-oxide (ANO) is a potent and highly selective inhibitor of vaccinia virus replication. We examined the impact of ANO on vaccinia virus macromolecular synthesis during synchronous infection of BSC40 cells. Viral DNA replication and viral late protein synthesis were blocked completely by A...

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Detalhes bibliográficos
Main Authors: Kane, E M, Shuman, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC189534/
https://ncbi.nlm.nih.gov/pubmed/7666536
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