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The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle.

Human immunodeficiency virus type 1 (HIV-1) infection causes profound immunological defects in afflicted patients. Various mechanisms have been proposed to account for the immune dysfunction in AIDS ultimately leading to loss of CD4+ T cells, including HIV-1 envelope-mediated syncytium formation, ap...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Jowett, J B, Planelles, V, Poon, B, Shah, N P, Chen, M L, Chen, I S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189529/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7666531/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.10.6304-6313.1995
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