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Rescue of “crippled” germinal center B cells from apoptosis by Epstein-Barr virus

Epstein-Barr virus (EBV) is associated with B-cell lymphomas such as Hodgkin lymphoma, Burkitt lymphoma, and post-transplantation lymphoma, which originate from clonal germinal center (GC) B cells. During the process of somatic hypermutation, GC B cells can acquire deleterious or nonsense mutations...

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Hlavní autoři: Mancao, Christoph, Altmann, Markus, Jungnickel, Berit, Hammerschmidt, Wolfgang
Médium: Artigo
Jazyk:Inglês
Vydáno: © 2005 by The American Society of Hematology 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895254/
https://ncbi.nlm.nih.gov/pubmed/16076866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2341
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