Pharmacodynamics of mycophenolate mofetil after nonmyeloablative conditioning and unrelated donor hematopoietic cell transplantation

The immunosuppressive drug mycophenolate mofetil (MMF) is used after nonmyeloablative hematopoietic cell transplantation (HCT); however, limited pharmacodynamic data are available. We evaluated plasma concentrations of mycophenolic acid (MPA), the active metabolite of MMF, and outcomes in 85 patient...

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Main Authors: Giaccone, Luisa, McCune, Jeannine S., Maris, Michael B., Gooley, Theodore A., Sandmaier, Brenda M., Slattery, John T., Cole, Scott, Nash, Richard A., Storb, Rainer F., Georges, George E.
Formato: Artigo
Idioma:Inglês
Publicado: © 2005 by The American Society of Hematology 2005
Assuntos:
Transplantation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895247/
https://ncbi.nlm.nih.gov/pubmed/16144801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2217
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