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Bcl-x(L) prevents apoptosis of late-stage erythroblasts but does not mediate the antiapoptotic effect of erythropoietin

The long form of B-cell lymphoma-x (Bcl-x(L)), an outer mitochondrial membrane protein, has been proposed to mediate the antiapoptotic action of erythropoietin on erythroid progenitor cells and to be necessary for heme synthesis in erythroblasts. Mice with conditional knockout of Bcl-x(L) (condition...

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Detalhes bibliográficos
Main Authors: Rhodes, Melissa M., Kopsombut, Prapaporn, Bondurant, Maurice C., Price, James O., Koury, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Hematology 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895223/
https://ncbi.nlm.nih.gov/pubmed/15899920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-11-4344
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