Amnionless function is required for cubilin brush-border expression and intrinsic factor-cobalamin (vitamin B(12)) absorption in vivo

Amnionless (AMN) and cubilin gene products appear to be essential functional subunits of an endocytic receptor called cubam. Mutation of either gene causes autosomal recessive Imerslund-Gräsbeck syndrome (I-GS, OMIM no. 261100) in humans, a disorder characterized by selective intestinal malabsorptio...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: He, Qianchuan, Madsen, Mette, Kilkenney, Adam, Gregory, Brittany, Christensen, Erik I., Vorum, Henrik, Højrup, Peter, Schäffer, Alejandro A., Kirkness, Ewen F., Tanner, Stephan M., de la Chapelle, Albert, Giger, Urs, Moestrup, Søren K., Fyfe, John C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society of Hematology 2005
Pynciau:
Red Cells
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895201/
https://ncbi.nlm.nih.gov/pubmed/15845892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-03-1197
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