B-cell recovery following rituximab-based therapy is associated with perturbations in stromal derived factor-1 and granulocyte homeostasis

The occurrence of delayed neutropenia following rituximab is poorly defined and of unknown cause. We hypothesized it may be related to perturbations of stromal derived factor-1 (SDF-1) and granulocyte homeostasis. Late-onset neutropenia (LON) was investigated in 130 patients with untreated aggressiv...

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Autors principals: Dunleavy, Kieron, Hakim, Frances, Kim, Hyun Kyung, Janik, John E., Grant, Nicole, Nakayama, Takayuki, White, Therese, Wright, George, Kwak, Larry, Gress, Ronald, Tosato, Giovanna, Wilson, Wyndham H.
Format: Artigo
Idioma:Inglês
Publicat: The American Society of Hematology 2005
Matèries:
Clinical Observations, Interventions, and Therapeutic Trials
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895166/
https://ncbi.nlm.nih.gov/pubmed/15718416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-08-3198
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