Association of klotho, bone morphogenic protein 6, and annexin A2 polymorphisms with sickle cell osteonecrosis

In patients with sickle cell disease, clinical complications including osteonecrosis can vary in frequency and severity, presumably due to the effects of genes that modify the pathophysiology initiated by the sickle mutation. Here, we examined the association of single nucleotide polymorphisms (SNPs...

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Autori principali: Baldwin, Clinton, Nolan, Vikki G., Wyszynski, Diego F., Ma, Qian-Li, Sebastiani, Paola, Embury, Stephen H., Bisbee, Alice, Farrell, John, Farrer, Lindsay, Steinberg, Martin H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: © 2005 by The American Society of Hematology 2005
Soggetti:
Red Cells
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895132/
https://ncbi.nlm.nih.gov/pubmed/15784727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-02-0548
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