Constitutive NF-κB and NFAT activation in aggressive B-cell lymphomas synergistically activates the CD154 gene and maintains lymphoma cell survival

Abnormalities in B-lymphocyte CD40 ligand (CD154) expression have been described for a number of immunologic diseases, including B-cell lymphomas. Although functional analysis of the CD154 gene and protein has been extensive, little is known about the mechanisms controlling CD154 expression in activ...

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Hlavní autoři: Pham, Lan V., Tamayo, Archito T., Yoshimura, Linda C., Lin-Lee, Yen-Chiu, Ford, Richard J.
Médium: Artigo
Jazyk:Inglês
Vydáno: © 2005 by The American Society of Hematology 2005
Témata:
Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895110/
https://ncbi.nlm.nih.gov/pubmed/16099873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-03-1167
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