L-selectin and β(7) integrin on donor CD4 T cells are required for the early migration to host mesenteric lymph nodes and acute colitis of graft-versus-host disease

The homing receptors L-selectin and α(4)β(7) integrin facilitate entry of T cells into the gut-associated organized lymphoid tissues such as the mesenteric lymph nodes and Peyer patches. We studied the impact of inactivation of genes encoding these receptors on the ability of purified donor CD4(+) T...

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Bibliographische Detailangaben
Hauptverfasser: Dutt, Suparna, Ermann, Joerg, Tseng, Diane, Liu, Yin Ping, George, Tracy I., Fathman, C. Garrison, Strober, Samuel
Format: Artigo
Sprache:Inglês
Veröffentlicht: © 2005 by The American Society of Hematology 2005
Schlagworte:
Transplantation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895109/
https://ncbi.nlm.nih.gov/pubmed/16105972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2339
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