L-selectin and β(7) integrin on donor CD4 T cells are required for the early migration to host mesenteric lymph nodes and acute colitis of graft-versus-host disease

The homing receptors L-selectin and α(4)β(7) integrin facilitate entry of T cells into the gut-associated organized lymphoid tissues such as the mesenteric lymph nodes and Peyer patches. We studied the impact of inactivation of genes encoding these receptors on the ability of purified donor CD4(+) T...

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Detalhes bibliográficos
Main Authors: Dutt, Suparna, Ermann, Joerg, Tseng, Diane, Liu, Yin Ping, George, Tracy I., Fathman, C. Garrison, Strober, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: © 2005 by The American Society of Hematology 2005
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895109/
https://ncbi.nlm.nih.gov/pubmed/16105972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-06-2339
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