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Trafficking of the major virulence factor to the surface of transfected P falciparum–infected erythrocytes

After invading human red blood cells (RBCs) the malaria parasite Plasmodium falciparum remodels the host cell by trafficking proteins to the RBC compartment. The virulence protein P falciparum erythrocyte membrane protein 1 (PfEMP1) is responsible for cytoadherence of infected cells to host endothel...

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Autori principali: Knuepfer, Ellen, Rug, Melanie, Klonis, Nectarios, Tilley, Leann, Cowman, Alan F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: © 2005 by The American Society of Hematology 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895071/
https://ncbi.nlm.nih.gov/pubmed/15692070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-12-4666
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