In vivo analysis of replication and immunogenicity of proviral clones of human T-lymphotropic virus type 1 with selective envelope surface-unit mutations

Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of adult T-cell lymphoma/leukemia (ATL). The HTLV-1 envelope gene exhibits limited variability when examined from infected individuals, but has not been tested using infectious clones of the virus in animal models. In vitro assays in...

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Dettagli Bibliografici
Autori principali: Silverman, Lee R., Phipps, Andrew J., Montgomery, Andy, Fernandez, Soledad, Tsukahara, Tomonori, Ratner, Lee, Lairmore, Michael D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: © 2005 by The American Society of Hematology 2005
Soggetti:
Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895059/
https://ncbi.nlm.nih.gov/pubmed/16046523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-03-1076
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