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Pharmacogenetics of outcome in children with acute lymphoblastic leukemia

Acquired genetic characteristics of acute lymphoblastic leukemia (ALL) cells are used to individualize therapy, whereas germ line genetic characteristics generally are not. We determined whether ALL outcome was related to 16 genetic polymorphisms affecting the pharmacodynamics of antileukemic agents...

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Main Authors: Rocha, Jose Claudio C., Cheng, Cheng, Liu, Wei, Kishi, Shinji, Das, Soma, Cook, Edwin H., Sandlund, John T., Rubnitz, Jeffrey, Ribeiro, Raul, Campana, Dario, Pui, Ching-Hon, Evans, William E., Relling, Mary V.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society of Hematology 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895006/
https://ncbi.nlm.nih.gov/pubmed/15713801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-11-4544
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