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An RNA interference model of RPS19 deficiency in Diamond-Blackfan anemia recapitulates defective hematopoiesis and rescue by dexamethasone: identification of dexamethasone-responsive genes by microarray

Diamond-Blackfan anemia (DBA), a congenital erythroblastopenia, is a model disease for the study of erythroid differentiation but is poorly understood. RPS19 is the only gene yet to have been associated with DBA, but its relevance to erythroid differentiation is unclear. The molecular basis for the...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Ebert, Benjamin L., Lee, Michele M., Pretz, Jennifer L., Subramanian, Aravind, Mak, Raymond, Golub, Todd R., Sieff, Colin A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The American Society of Hematology 2005
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895002/
https://ncbi.nlm.nih.gov/pubmed/15755903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-08-3313
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