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Rofecoxib modulates multiple gene expression pathways in a clinical model of acute inflammatory pain

New insights into the biological properties of cyclooxygenase-2 (COX-2) and its response pathway challenge the hypothesis that COX-2 is simply pro-inflammatory and inhibition of COX-2 solely prevents the development of inflammation and ameliorates inflammatory pain. The present study performed a com...

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Autors principals: Wang, Xiao-Min, Wu, Tian-Xia, Hamza, May, Ramsay, Edward S., Wahl, Sharon M., Dionne, Raymond A.
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894940/
https://ncbi.nlm.nih.gov/pubmed/17070997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2006.09.011
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