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Expression of alpha v beta 5 integrin is necessary for efficient adenovirus-mediated gene transfer in the human airway.

Recombinant adenoviruses are being evaluated for gene therapy of cystic fibrosis lung disease with the goal of reconstituting the expression of the cystic fibrosis transmembrane conductance regulator in pulmonary epithelia by direct administration of the virus into the airway. The therapeutic potent...

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Bibliografske podrobnosti
izdano v:J Virol
Principais autores: Goldman, M J, Wilson, J M
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1995
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189490/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7545239/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.10.5951-5958.1995
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