Relative beta-lactamase- and transpeptidase-inhibitory activities of the new quinolone WIN-57273 in Staphylococcus aureus.

The new quinolone WIN-57273 was shown to inhibit Staphylococcus aureus beta-lactamase activity noncompetitively in vitro with an apparent Ki value of 0.5 mM. MICs of penicillin G for a highly quinolone-resistant, beta-lactamase-negative strain in the presence of exogenous beta-lactamase decreased co...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Furet, Y X, Lucain, C, Pechère, J C
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189483/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1323958/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.4.894
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