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Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution
BACKGROUND: Non-ribosomal peptide synthetases (NRPSs) are large multimodular enzymes that synthesize a wide range of biologically active natural peptide compounds, of which many are pharmacologically important. Peptide bond formation is catalyzed by the Condensation (C) domain. Various functional su...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1894796/ https://ncbi.nlm.nih.gov/pubmed/17506888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-7-78 |
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