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The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique

AIMS: To investigate whether the drug–drug interaction between fexofenadine and ketoconazole is localized to efflux transport proteins of the small intestine, and to determine and classify the effective jejunal permeability (P(eff)) of fexofenadine according to the Biopharmaceutics Classification Sy...

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Autors principals: Tannergren, Christer, Knutson, Tina, Knutson, Lars, Lennernäs, Hans
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894734/
https://ncbi.nlm.nih.gov/pubmed/12580990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01722.x
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