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The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique

AIMS: To investigate whether the drug–drug interaction between fexofenadine and ketoconazole is localized to efflux transport proteins of the small intestine, and to determine and classify the effective jejunal permeability (P(eff)) of fexofenadine according to the Biopharmaceutics Classification Sy...

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Detalhes bibliográficos
Main Authors: Tannergren, Christer, Knutson, Tina, Knutson, Lars, Lennernäs, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894734/
https://ncbi.nlm.nih.gov/pubmed/12580990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01722.x
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