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Fast and Accurate Estimation of the Population-Scaled Mutation Rate, θ, From Microsatellite Genotype Data

We present a new approach for estimation of the population-scaled mutation rate, θ, from microsatellite genotype data, using the recently introduced “product of approximate conditionals” framework. Comparisons with other methods on simulated data demonstrate that this new approach is attractive in t...

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Detalhes bibliográficos
Main Authors: RoyChoudhury, Arindam, Stephens, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894599/
https://ncbi.nlm.nih.gov/pubmed/17579241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.049080
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