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Methylation of the p16(INK4a) promoter region in telomerase immortalized human keratinocytes co-cultured with feeder cells

Human keratinocytes grown in co-culture with fibroblast feeder cells have an extended in vitro lifespan and delayed accumulation of the tumor suppressor protein p16(INK4a) when compared to the same cells grown on tissue culture plastic alone. Previous studies have indicated that human keratinocytes...

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Hlavní autoři: Darbro, BW, Lee, KM, Nguyen, NK, Domann, FE, Klingelhutz, AJ
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1894570/
https://ncbi.nlm.nih.gov/pubmed/16767161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1209729
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