The amino terminus of Tax is required for interaction with the cyclic AMP response element binding protein.

Tax of human T-cell leukemia virus type 1 was analyzed for interaction with the cyclic AMP response element binding protein (CREB) in vitro with and without Tax response element DNA. Mutations in the carboxy terminus of Tax (L296G and L320G) did not affect binding to CREB and led to supershifts. In...

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Bibliographic Details
Main Authors: Goren, I, Semmes, O J, Jeang, K T, Moelling, K
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC189446/
https://ncbi.nlm.nih.gov/pubmed/7637025
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