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Involvement of the V1/V2 variable loop structure in the exposure of human immunodeficiency virus type 1 gp120 epitopes induced by receptor binding.

The binding of human immunodeficiency virus type 1 (HIV-1) to the cellular receptor CD4 has been suggested to induce conformational changes in the viral envelope glycoproteins that promote virus entry. Conserved, discontinuous epitopes on the HIV-1 gp120 glycoprotein recognized by the 17b, 48d, and...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Wyatt, R, Moore, J, Accola, M, Desjardin, E, Robinson, J, Sodroski, J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189432/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7543586/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.9.5723-5733.1995
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