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Differential antigen burden modulates the gamma interferon but not the immunoglobulin response in mice that vary in susceptibility to Sendai virus pneumonia.

Sendai virus, a paramyxovirus which causes murine pneumonia, grew to approximately 10-fold higher titers and was cleared less rapidly from the lungs of 129/J (129) than H-2b-compatible C57BL/6J (B6) mice. The more susceptible 129 mice also made higher titers of gamma interferon (IFN-gamma) and immun...

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Bibliographic Details
Published in:J Virol
Main Authors: Mo, X Y, Sangster, M, Sarawar, S, Coleclough, C, Doherty, P C
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1995
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189415/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7637005/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.9.5592-5598.1995
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