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Metabolism of S-1108, a new oral cephem antibiotic, and metabolic profiles of its metabolites in humans.

The metabolism and pharmacokinetics of pivalic acid, a major metabolite of S-1108, were studied with three healthy volunteers. Concentrations of S-1006 (the active compound), pivalic acid, and pivaloylcarnitine in plasma and urine were measured after administration of S-1108. Recoveries in urine at...

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Hlavní autoři: Totsuka, K, Shimizu, K, Konishi, M, Yamamoto, S
Médium: Artigo
Jazyk:Inglês
Vydáno: 1992
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC189391/
https://ncbi.nlm.nih.gov/pubmed/1503437
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