Human cytomegalovirus upregulates NF-kappa B activity by transactivating the NF-kappa B p105/p50 and p65 promoters.

Míreanna Comhchosúla

• Induction of the transcription factor Sp1 during human cytomegalovirus infection mediates upregulation of the p65 and p105/p50 NF-kappaB promoters.
  le: Yurochko, A D, et al.
  Foilsithe: (1997)
• A novel mitogen-inducible gene product related to p50/p105-NF-kappa B participates in transactivation through a kappa B site.
  le: Bours, V, et al.
  Foilsithe: (1992)
• The NF-kappa B p50 precursor, p105, contains an internal I kappa B-like inhibitor that preferentially inhibits p50.
  le: Liou, H C, et al.
  Foilsithe: (1992)
• I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding.
  le: Ganchi, P A, et al.
  Foilsithe: (1992)
• NF-kappa B contacts DNA by a heterodimer of the p50 and p65 subunit.
  le: Urban, M B, et al.
  Foilsithe: (1991)