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Failure of the bovine papillomavirus to transform mouse embryo fibroblasts with a targeted disruption of the insulin-like growth factor I receptor genes.

Mouse embryo cells with a targeted disruption of the insulin-like growth factor I receptor (IGF-IR) genes (R- cells) are refractory to transformation by the simian virus 40 large T antigen and/or an activated and overexpressed Ras, both of which readily transform cells from wild-type littermate embr...

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Bibliografische gegevens
Hoofdauteurs: Morrione, A, DeAngelis, T, Baserga, R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1995
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC189367/
https://ncbi.nlm.nih.gov/pubmed/7636972
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