A single amino acid change in the cytoplasmic domain of the simian immunodeficiency virus transmembrane molecule increases envelope glycoprotein expression on infected cells.

We have described a virus termed CP-MAC, derived from the BK28 molecular clone of simian immunodeficiency virus, that was remarkable for its ability to infect Sup-T1 cells with rapid kinetics, cell fusion, and CD4 down-modulation (C. C. LaBranche, M. M. Sauter, B. S. Haggarty, P. J. Vance, J. Romano...

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Bibliographic Details
Main Authors: LaBranche, C C, Sauter, M M, Haggarty, B S, Vance, P J, Romano, J, Hart, T K, Bugelski, P J, Marsh, M, Hoxie, J A
Format: Artigo
Language:Inglês
Published: 1995
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC189351/
https://ncbi.nlm.nih.gov/pubmed/7636963
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