Selection of a single amino acid substitution in the hemagglutinin molecule by chicken eggs can render influenza A virus (H3) candidate vaccine ineffective.

This study investigated whether a single amino acid change in the hemagglutinin (HA) molecule influenced the efficacy of formalin-inactivated influenza A (H3N1) vaccine candidates derived from high-growth reassortants between the standard donor of high-yield genes (A/PR/8/34 [H1N1]) and host cell va...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Kodihalli, S, Justewicz, D M, Gubareva, L V, Webster, R G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189303/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7609057/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.8.4888-4897.1995
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