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Virstatin inhibits dimerization of the transcriptional activator ToxT
The development of antimicrobials is critical in this time of increasing antibiotic resistance of most clinically relevant bacteria. To date, all current antibiotics focus on inhibiting crucial enzymatic activities of their protein targets (i.e., trimethoprim for dihydrofolate reductase), thus disru...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1892951/ https://ncbi.nlm.nih.gov/pubmed/17283330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611643104 |
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