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vpr deletion mutant of simian immunodeficiency virus induces AIDS in rhesus monkeys.

In previous experiments, animals infected with SIVmac239 containing a point mutation in the vpr and nef genes developed AIDS-like symptoms after early reversion of the vpr and nef genes. Here we show that two animals in which the nef gene but not the vpr gene had reverted in the first few months did...

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Autors principals: Hoch, J, Lang, S M, Weeger, M, Stahl-Hennig, C, Coulibaly, C, Dittmer, U, Hunsmann, G, Fuchs, D, Müller, J, Sopper, S
Format: Artigo
Idioma:Inglês
Publicat: 1995
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC189293/
https://ncbi.nlm.nih.gov/pubmed/7609047
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