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A catalytic beacon sensor for uranium with parts-per-trillion sensitivity and millionfold selectivity

Here, we report a catalytic beacon sensor for uranyl (UO(2)(2+)) based on an in vitro-selected UO(2)(2+)-specific DNAzyme. The sensor consists of a DNA enzyme strand with a 3′ quencher and a DNA substrate with a ribonucleotide adenosine (rA) in the middle and a fluorophore and a quencher at the 5′ a...

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Autori principali: Liu, Juewen, Brown, Andrea K., Meng, Xiangli, Cropek, Donald M., Istok, Jonathan D., Watson, David B., Lu, Yi
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892917/
https://ncbi.nlm.nih.gov/pubmed/17284609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607875104
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