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Direct measurement of force generation by actin filament polymerization using an optical trap

Actin filament polymerization generates force for protrusion of the leading edge in motile cells. In protrusive structures, multiple actin filaments are arranged in cross-linked webs (as in lamellipodia or pseudopodia) or parallel bundles (as in filopodia). We have used an optical trap to directly m...

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Bibliographic Details
Main Authors: Footer, Matthew J., Kerssemakers, Jacob W. J., Theriot, Julie A., Dogterom, Marileen
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892916/
https://ncbi.nlm.nih.gov/pubmed/17277076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607052104
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