Vaccination with recombinant vaccinia viruses expressing ICP27 induces protective immunity against herpes simplex virus through CD4+ Th1+ T cells.

This study was designed to evaluate the efficacy and mechanisms of protection mediated by recombinant vaccinia viruses encoding immediate-early (IE) proteins of herpes simplex virus type 2 (HSV-2). Three mouse strains were immunized against the IE proteins ICP27, ICP0, and ICP4, and mice were challe...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Manickan, E, Francotte, M, Kuklin, N, Dewerchin, M, Molitor, C, Gheysen, D, Slaoui, M, Rouse, B T
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1995
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189277/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7609036/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.8.4711-4716.1995
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