The cardiovirulent phenotype of coxsackievirus B3 is determined at a single site in the genomic 5' nontranslated region.

We report the construction of chimeric coxsackievirus B3 (CVB3) strains in which sequences of an infectious cDNA copy of a noncardiovirulent CVB3 genome were replaced by the homologous sequences from a cardiovirulent CVB3 genome to identify which of 10 predicted genetic sites determine cardiovirulen...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Tu, Z, Chapman, N M, Hufnagel, G, Tracy, S, Romero, J R, Barry, W H, Zhao, L, Currey, K, Shapiro, B
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189260/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7609025/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.8.4607-4618.1995
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