Regulation of RKIP binding to the N-region of the Raf-1 kinase

The Raf kinase inhibitory protein (RKIP) binds to Raf-1 interfering with binding of the MEK substrate and potentially also Raf-1 activation. In response to mitogen stimulation RKIP dissociates from Raf-1 and later re-associates. Here, using a combination of mutational approaches, biochemical studies...

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Hlavní autoři: Park, Sungdae, Rath, Oliver, Beach, Sandy, Xiang, Xiaoqin, Kelly, Sharon M., Luo, Zhijun, Kolch, Walter, Yeung, Kam C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892598/
https://ncbi.nlm.nih.gov/pubmed/17097642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2006.10.054
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