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Yin6, a fission yeast Int6 homolog, complexes with Moe1 and plays a role in chromosome segregation

The INT6 gene has been implicated in human breast cancer formation, but its function is unknown. We isolated an Int6 homolog from fission yeast, Yin6, by its binding to a conserved protein in the Ras pathway, Moe1. Yin6 and Moe1 converge on the same protein complex to promote microtubule instability...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yen, Hsueh-Chi S., Chang, Eric C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC18925/
https://ncbi.nlm.nih.gov/pubmed/11121040
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