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Activator of G protein signaling 3 is a guanine dissociation inhibitor for Gα(i) subunits

Activator of G protein signaling 3 (AGS3) is a newly identified protein shown to act at the level of the G protein itself. AGS3 belongs to the GoLoco family of proteins, sharing the 19-aa GoLoco motif that is a Gα(i/o) binding motif. AGS3 interacts only with members of the Gα(i/o) subfamily. By surf...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: De Vries, Luc, Fischer, Thierry, Tronchère, Hélène, Brothers, Greg M., Strockbine, Bentley, Siderovski, David P., Farquhar, Marilyn Gist
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18924/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11121039/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.26.14364
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