Quantifying Telomere Lengths of Human Individual Chromosome Arms by Centromere-Calibrated Fluorescence in Situ Hybridization and Digital Imaging

Telomere length analysis has aroused considerable interest in biology and oncology. However, most published data are pan-genomic Southern-blot-based estimates. We developed T/C-FISH (telomere/centromere-FISH), allowing precise measurement of individual telomeres at every single chromosome arm. Metap...

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Detalhes bibliográficos
Main Authors: Perner, Sven, Brüderlein, Silke, Hasel, Cornelia, Waibel, Irena, Holdenried, Alexandra, Ciloglu, Neslisah, Chopurian, Heiko, Nielsen, Kirsten Vang, Plesch, Andreas, Högel, Josef, Möller, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2003
Assuntos:
Technical Advance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892442/
https://ncbi.nlm.nih.gov/pubmed/14578175
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