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B Lymphocyte-Specific c-Myc Expression Stimulates Early and Functional Expansion of the Vasculature and Lymphatics during Lymphomagenesis

Expression of the c-myc proto-oncogene is deregulated in many human cancers. We examined the role of c-Myc in stimulating angiogenesis and lymphangiogenesis in a highly metastatic murine model of Burkitt’s lymphoma (Eμ-c-myc), where c-Myc is expressed exclusively in B lymphocytes. Immunohistochemica...

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Auteurs principaux: Ruddell, Alanna, Mezquita, Pau, Brandvold, Kimberly A., Farr, Andrew, Iritani, Brian M.
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2003
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892400/
https://ncbi.nlm.nih.gov/pubmed/14633598
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