MKK3 Mitogen-Activated Protein Kinase Pathway Mediates Carbon Monoxide-Induced Protection Against Oxidant-Induced Lung Injury

The stress-inducible gene heme oxygenase (HO-1) has previously been shown to provide cytoprotection against oxidative stress. The mechanism(s) by which HO-1 provides this cytoprotection is poorly understood. We demonstrate here that carbon monoxide (CO), a byproduct released during the degradation o...

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Main Authors: Otterbein, Leo E., Otterbein, Sherrie L., Ifedigbo, Emeka, Liu, Fang, Morse, Danielle E., Fearns, Colleen, Ulevitch, Richard J., Knickelbein, Roy, Flavell, Richard A., Choi, Augustine M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2003
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Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1892354/
https://ncbi.nlm.nih.gov/pubmed/14633627
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